Reflux Nephropathy Update 1983 (Contributions to Nephrology) by C. J. Hodson

Cover of: Reflux Nephropathy Update | C. J. Hodson

Published by S. Karger AG (Switzerland) .

Written in English

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  • Renal medicine,
  • Nephrology,
  • Kidney Diseases,
  • Medical / Nursing

Edition Notes

Book details

ContributionsJ. Winberg (Editor)
The Physical Object
Number of Pages388
ID Numbers
Open LibraryOL12929495M
ISBN 103805538073
ISBN 109783805538077

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Reflux nephropathy is kidney damage (nephropathy) due to urine flowing backward (reflux) from the bladder toward the kidneys; the latter is called vesicoureteral reflux (VUR). Longstanding VUR can result in small and scarred kidneys during the first five years of life in affected children.

The end results of reflux nephropathy can include high blood pressure, excessive protein loss in the Specialty: Urology. Reflux Nephropathy Update: (Contributions to Nephrology, Vol. 39): Medicine & Health Science Books @ A Family History of Vesicoureteral Reflux.

Frequent Episodes of Urinary Tract Infections. Pregnancy-Women with reflux nephropathy normally have successful r, there is an increased risk of urine infection during pregnancy. If there is protein in the urine or scarring on the kidneys, there is an increased risk of high blood pressure, and this requires careful.

Genre/Form: Congress: Additional Physical Format: Online version: Reflux nephropathy update, Basel ; New York: Karger, (OCoLC) Online version. Reflux nephropathy is a condition in which the kidneys are damaged by the backward flow of urine into the kidney.

Urine flows from each kidney through tubes called ureters and into the bladder. When the bladder is full, it squeezes and sends the urine out through the urethra.

No urine should flow back into the ureter when the bladder is squeezing. ISBN: OCLC Number: Notes: Proceedings of a workshop sponsored by the Kroc Foundation, and held near Santa Barbara, Calif., Oct.

Reflux nephropathy is kidney scarring caused by urine flowing backward from the bladder into a ureter and toward a kidney.

(See also Overview of Kidney Filtering Disorders.) Normally, where the bladder and the ureter join, the ureter tunnels slightly sideways through the bladder wall. Reflux nephropathy: Introduction. Reflux nephropathy: A condition which is characterized by reflux of urine from the bladder back up the ureters.

More detailed information about the symptoms, causes, and treatments of Reflux nephropathy is available. Reflux nephropathy is kidney scarring caused by urine flowing backward from the bladder into a ureter and toward a kidney.

(See also Overview of Kidney Filtering Disorders.) Normally, where the bladder and the ureter join, the ureter tunnels slightly sideways through the bladder wall. The muscles of the bladder wall help keep the end of the. This is called reflux nephropathy. Reflux can occur in people whose ureters do not attach properly to the bladder or whose valves do not work well.

Children may be born with this problem or may have other birth defects of the urinary system that cause reflux nephropathy. Reflux nephropathy can occur with other conditions that lead to a blockage.

INTRODUCTION. Vesicoureteral reflux (VUR) is the retrograde passage of urine from the bladder into the upper urinary tract. The clinical significance of VUR has been based on the premise that VUR predisposes patients to acute pyelonephritis by transporting bacteria from the bladder to the kidney and recurrent urinary tract infection, which may lead to renal scarring, hypertension.

Kirk P. Conrad, S. Ananth Karumanchi, in Seldin and Giebisch's The Kidney (Fifth Edition), Reflux Nephropathy and Other Tubulointerstitial Disorders. Reflux nephropathy is a disease that begins during childhood and thus is present in a substantial number of pregnant women. The natural history of this disorder during pregnancy was once disputed, but two reports.

Historically, reflux nephropathy was initially understood to be renal parenchymal lesions found in the kidneys of patients who experienced a febrile UTI or pyelonephritis in the face of VUR.A classic cascade of events due to bacterial infection of the kidneys was described by Roberts ().Schematically, the process of renal scarring initiates with colonization of the urinary tract by.

Reflux nephropathy is renal scarring presumably induced by vesicoureteral reflux of infected urine into the renal parenchyma. The diagnosis is suspected in children with urinary tract infections or a family history of reflux nephropathy, or if a prenatal ultrasound shows hydronephrosis.

Reflux nephropathy is also associated with interstitial Tamm-Horsfall protein (THP) deposition or THP reflux into the Bowman capsule (Figures (Figures1D 1 D and F) due to combined VUR and IRR associated with UTI, or permanently high intravesical pressures in human VUR patie19 or animal reflux nephropathy models.

20 In kidney transplant settings, Kobayashi et al 17 Cited by: 2. Renal ultrasonography (RUS) and voiding cystourethrography (VCUG) are the preferred radiologic examination methods.

[1, 2, 3] The 2 procedures provide complementary helps in evaluating the upper urinary tract (kidneys and proximal portion of the collecting system) for anomalies, masses, calcification, hydronephrosis, and size and can. Reflux nephropathy can also occur from swelling of the ureters after a kidney transplant or from injury to the ureter.

Risk factors for reflux nephropathy include: Abnormalities of the urinary tract Personal or family history of vesicoureteral reflux Repeat urinary tract infections; Symptoms Some people have no symptoms of reflux nephropathy.

Contrast Enhanced Ultrasound for Evaluation of Reflux Nephropathy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.

Primary vesicoureteral reflux (VUR) is the commonest congenital urological abnormalities in children, which has been associated with an increased risk of urinary tract infection (UTI) and renal scarring, also called reflux nephropathy (RN).

In children, RN is diagnosed mostly after UTI (acquired RN) or during follow-up for antenatally diagnosed Cited by:   > Reflux is the abnormal passage of urine back up the ureter and may occur on one or both sides. It is managed by the urologist primarily.

Treatment plans are individualized according to age/sex, grade of reflux, associated urologic problems, the. Abstract. In the last few years reflux nephropathy has elicited a growing interest not only among pediatricians, because of the high prevalence of the disease in children presenting with urinary tract infection and of its relevance in causing end stage renal failure, but also among nephrologists, due to an increasing rate of discovery of this disease in adults.

In young children, acquired reflux nephropathy is more common in girls than boys, with a ratio of 4 to 1, similar to the sex prevalence in patients with VUR detected after evaluation for a UTI.

In older children, the incidence of reflux nephropathy is equivalent among the sexes, but males appear to be more severely affected.

Reflux was absent in of the reimplanted ureters (%) at the end of 5 years. No patient underwent reoperation for reflux. Book Review: Reflux. Vesicoureteral reflux may be suggested by fetal ultrasound in pregnancy (in which renal pelvis dilation is observed) or after urinary tract infection (UTI) in childhood.

The presence of VUR increases the risk of upper tract UTI, and the two together can cause renal injury leading to scarring of the kidney termed reflux nephropathy (RN).

Reflux nephropathy i.e. renal scarring associated with vesico-ureteric reflux (VUR) and urinary tract infection (UTI) was originally considered an acquired disease. The renal scarring seems to get worse with recurrent urine infections especially in the by: reflux nephropathy: [ nĕ-frop´ah-the ] 1.

any disease of the kidneys. adj., adj nephropath´ic. any disease of the kidneys; see also nephritis. Called also nephrosis.

adj., adj nephropath´ic. AIDS nephropathy former name for HIV-associated nephropathy. analgesic nephropathy interstitial nephritis with renal papillary necrosis, seen in.

Reflux nephropathy can also occur from swelling of the ureters after a kidney transplant or from injury to the ureter. Risk factors for reflux nephropathy include: Abnormalities of the urinary tract; Personal or family history of vesicoureteral reflux; Repeat urinary tract infections; Symptoms.

Some people have no symptoms of reflux nephropathy. Forty-five percent of gene carriers will have vesicoureteric reflux and/or reflux nephropathy as adults and 15% will develop renal failure, compared to % and %, respectively, for those Author: Constantinos J Stefanidis.

Vesicoureteral reflux (VUR) is characterized by the retrograde flow of urine from the bladder to the kidneys. VUR may be associated with urinary tract infection (UTI), hydronephrosis, and abnormal kidney development (renal dysplasia).

Vesicoureteric reflux (VUR) describes the flow of urine from the bladder into the upper urinary tract when the ureterovesical junction fails to perform as a one-way valve. Most commonly, VUR is primary, though it can be secondary to bladder outflow obstruction and can occur in several multiorgan congenital disorders.

There is good evidence of a genetic basis with a greatly. Reflux Nephropathy is the condition of kidney damage due to the backward flow of urine from bladder into kidneys. The disease is more common in children and causes inveterate childhood abnormality in urinary tract and the long term disease is alleged to cause chronic pyelonephritis, high blood pressure, excessive protein loss, obstructive uropathy and kidney failure/5(28).

Vesicoureteric Reflux and Reflux Nephropathy. Reflux nephropathy is the scarring and damage caused to the kidneys by reverse flow of urine from the. Vesicoureteral reflux and reflux nephropathy Overview Vesicoureteral reflux (VUR) – also called vesicoureteric reflux – is quite a common condition, especially in babies and young children.

When children with VUR go for a wee, some urine refluxes, or passes back up the wrong way, towards one or both kidneys. Reflux Nephropathy MICHAEL and CHULANANDA EKERA Renal Unit, Great Ormond Street Hospitalfor Children and Department ofNephrourology, Institute ofChild Health, London, United Kingdom.

Reflux nephropathy isaterm thatwasproposed in by Bailey todescribe the coarse renal scarring ofone onboth. Primary vesicoureteric reflux is often associated with kidney damage, mostly referred to as reflux nephropathy. It has been traditionally assumed that in primary vesicoureteric reflux kidney damage results from reflux of infected urine into the renal tissue but recent observations indicate that kidney damage sometimes occurs : Laura Santoro, Alessandra Ferrarini, Laura Crosazzo, Mario G.

Bianchetti. Pediatric Urinary Tract Infection and Reflux and reflux nephropathy is an important cause of end-stage renal disease in children and an update. Clin Pediatr [Phila].

;–4. Cited by: Although it appears that reflux management has improved outcomes for some children such that the incidence of reflux-associated nephropathy continues to decline, recent urologic literature suggests that the natural history of VUR does not follow a uniform pathway, and many children with reflux do not benefit from either diagnosis or treatment [4].

Retrograde (reflux) nephropathy, a form of obstructive nephropathy, is related to a backflow phenomenon characterized by small clusters of dilated tubules that ascend from the papilla to the cortex and are due to increased urine reflux resulting from changes in the lower urinary tract (Figure 1 and Figure 2).

Lesions of the lower urinary tract. Kidney – Nephropathy, Obstructive. Comment: Obstructive nephropathy may result from inflammation associated with deposition of crystals, retrograde nephropathy, or a lower urinary tract outflow blockage.

Whatever the cause, similar morphologic changes can be observed. Retrograde (reflux) nephropathy, a form of obstructiveFile Size: KB. Treatments for Reflux nephropathy including drugs, prescription medications, alternative treatments, surgery, and lifestyle changes.

Introduction. Primary vesicoureteric reflux (VUR) (OMIM # ) is a common disorder in children, and shows a strong familial association ().VUR is the regurgitation of urine from the bladder into the ureter and kidney ().The true incidence of VUR in an unselected population has not been established, although current estimates suggest it is between 1/ Cited by: It can, if severe.

How much kidney damage reflux nephropathy can cause depends on the degree of reflux and the number and severity of kidney infections that may result. These insults can scar the affected kidney, diminishing kidney function.

Chronic kidney failure means that a person's overall kidney function is not adequate, and can occur if both kidneys are severely .Reflux Nephropathy. Also known as chronic atrophic pyelonephritis, relux nephropathy is the result of parenchymal scarring caused by reflux of either sterile or infected urine leads to renal atrophy with an irregular contour.

Contour abnormality should be differentiated from fetal lobation.

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